AIMC Topic: Radiotherapy Dosage

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Deep learning-based applicator selection between Syed and T&O in high-dose-rate brachytherapy for locally advanced cervical cancer: a retrospective study.

Physics in medicine and biology
High-dose-rate (HDR) brachytherapy is integral to the standard-of-care for locally advanced cervical cancer (LACC). Currently, selection of brachytherapy applicators relies on physician's clinical experience, which can lead to variability in treatmen...

Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.

Frontiers in public health
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.

Evaluation of deliverable artificial intelligence-based automated volumetric arc radiation therapy planning for whole pelvic radiation in gynecologic cancer.

Scientific reports
This study aimed to develop a deep learning (DL)-based deliverable whole pelvic volumetric arc radiation therapy (VMAT) for patients with gynecologic cancer using a prototype DL-based automated planning support system, named RatoGuide, to evaluate it...

Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments.

Journal of applied clinical medical physics
Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra-hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter-fraction variabil...

Reinforcement learning-driven automated head and neck simultaneous integrated boost (SIB) radiation therapy: flexible treatment planning aligned with clinical preferences.

Physics in medicine and biology
Head-and-neck simultaneous integrated boost (SIB) treatment planning using intensity modulated radiation therapy is particularly challenging due to the proximity to organs-at-risk. Depending on the specific clinical conditions, different parotid-spar...

A machine learning toolkit assisted approach for IMRT fluence map optimization: feasibility and advantages.

Biomedical physics & engineering express
. Traditional machine learning (ML) and deep learning (DL) applications in treatment planning rely on complex model architectures and large, high-quality training datasets. However, they cannot fully replace the conventional optimization process. Thi...

Two-step beam geometry optimization for volumetric modulated arc therapy gantry angles in breast treatments.

Medical physics
BACKGROUND: In partial arc volumetric modulated arc therapy (VMAT) for treating breast cancer, setting up the limiting gantry positions of the treatment machine is a nontrivial yet repetitive and time-consuming task during planning. Templatized solut...

Towards improved prescription metrics in novel radiotherapy techniques: a machine learning study.

Physics in medicine and biology
FLASH radiotherapy (RT), microbeam RT (MRT) and minibeam RT (MBRT) are novel RT techniques that have been shown to reduce normal tissue complication probabilities, by modulating the dose distributions through different parameters in space and time. T...

Evaluating the dosimetric and positioning accuracy of a deep learning based synthetic-CT model for liver radiotherapy treatment planning.

Biomedical physics & engineering express
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...

Portal dose image prediction using Monte Carlo generated transmission energy fluence maps of dynamic radiotherapy treatment plans: a deep learning approach.

Biomedical physics & engineering express
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...