Capsule robot pose and mechanism state detection in ultrasound using attention-based hierarchical deep learning.

Journal: Scientific reports
Published Date:

Abstract

Ingestible robotic capsules with locomotion capabilities and on-board sampling mechanism have great potential for non-invasive diagnostic and interventional use in the gastrointestinal tract. Real-time tracking of capsule location and operational state is necessary for clinical application, yet remains a significant challenge. To this end, we propose an approach that can simultaneously determine the mechanism state and in-plane 2D pose of millimeter capsule robots in an anatomically representative environment using ultrasound imaging. Our work proposes an attention-based hierarchical deep learning approach and adapts the success of transfer learning towards solving the multi-task tracking problem with limited dataset. To train the neural networks, we generate a representative dataset of a robotic capsule within ex-vivo porcine stomachs. Experimental results show that the accuracy of capsule state classification is 97%, and the mean estimation errors for orientation and centroid position are 2.0 degrees and 0.24 mm (1.7% of the capsule's body length) on the hold-out test set. Accurate detection of the capsule while manipulated by an external magnet in a porcine stomach and colon is also demonstrated. The results suggest our proposed method has the potential for advancing the wireless capsule-based technologies by providing accurate detection of capsule robots in clinical scenarios.

Authors

  • Xiaoyun Liu
    Department of General Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Daniel Esser
    Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, 37235, USA.
  • Brandon Wagstaff
    University of Toronto Institute of Aerospace Studies, University of Toronto, Toronto, ON, M5S1A8, Canada.
  • Anna Zavodni
    Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON, M5S1A8, Canada.
  • Naomi Matsuura
    Department of Materials Science and Engineering and Institute of Biomedical Engineering, University of Toronto, Toronto, ON, M5S1A8, Canada.
  • Jonathan Kelly
    Flatiron Health Inc, New York, New York.
  • Eric Diller
    Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, M5S 3G8 Canada.