Artificial Intelligence in Brain Tumor Imaging: A Step toward Personalized Medicine.

Journal: Current oncology (Toronto, Ont.)
Published Date:

Abstract

The application of artificial intelligence (AI) is accelerating the paradigm shift towards patient-tailored brain tumor management, achieving optimal onco-functional balance for each individual. AI-based models can positively impact different stages of the diagnostic and therapeutic process. Although the histological investigation will remain difficult to replace, in the near future the radiomic approach will allow a complementary, repeatable and non-invasive characterization of the lesion, assisting oncologists and neurosurgeons in selecting the best therapeutic option and the correct molecular target in chemotherapy. AI-driven tools are already playing an important role in surgical planning, delimiting the extent of the lesion (segmentation) and its relationships with the brain structures, thus allowing precision brain surgery as radical as reasonably acceptable to preserve the quality of life. Finally, AI-assisted models allow the prediction of complications, recurrences and therapeutic response, suggesting the most appropriate follow-up. Looking to the future, AI-powered models promise to integrate biochemical and clinical data to stratify risk and direct patients to personalized screening protocols.

Authors

  • Maurizio Cè
    Postgraduate School in Radiodiagnostics, 9304Università degli Studi di Milano, Milan, Italy.
  • Giovanni Irmici
    Postgraduation School in Radiodiagnostics, Università Degli Studi di Milano, Via Festa del Perdono 7, 20122, Milan, Italy.
  • Chiara Foschini
    Postgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy.
  • Giulia Maria Danesini
    Postgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy.
  • Lydia Viviana Falsitta
    Postgraduation School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, Italy.
  • Maria Lina Serio
    Postgraduation School in Radiodiagnostics, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.
  • Andrea Fontana
  • Carlo Martinenghi
    Radiology Department, San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.
  • Giancarlo Oliva
    Radiology Department, Fatebenefratelli Hospital, ASST Fatebenefratelli Sacco, Piazza Principessa Clotilde 3, 20121 Milan, Italy.
  • Michaela Cellina
    Radiology Department, Fatebenefratelli Hospital, Milano, Italy.