Topical Tranexamic Acid Reduces Blood Loss in Minimally Invasive Total Knee Arthroplasty Receiving Rivaroxaban.

Journal: BioMed research international
PMID: 29410968

Abstract

BACKGROUND: It is unclear whether topical (intra-articular) or intravenous TXA reduces blood loss in minimally invasive TKA patients receiving a direct oral anticoagulant for thromboprophylaxis. This study is to investigate whether TXA given intravenously or intra-articularly is effective in reducing blood loss in minimally invasive TKA patients using rivaroxaban for thromboprophylaxis.

Authors

  • Shih-Hsiang Yen
    Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.
  • Po-Chun Lin
    Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.
  • Bradley Chen
    Institute of Public Health, National Yang Ming University, Taipei, Taiwan.
  • Chung-Chen Huang
    Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.
  • Jun-Wen Wang
    Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.

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