Improving Generalization by Learning Geometry-Dependent and Physics-Based Reconstruction of Image Sequences.

Journal: IEEE transactions on medical imaging
Published Date:

Abstract

Deep neural networks have shown promise in image reconstruction tasks, although often on the premise of large amounts of training data. In this paper, we present a new approach to exploit the geometry and physics underlying electrocardiographic imaging (ECGI) to learn efficiently with a relatively small dataset. We first introduce a non-Euclidean encoding-decoding network that allows us to describe the unknown and measurement variables over their respective geometrical domains. We then explicitly model the geometry-dependent physics in between the two domains via a bipartite graph over their graphical embeddings. We applied the resulting network to reconstruct electrical activity on the heart surface from body-surface potentials. In a series of generalization tasks with increasing difficulty, we demonstrated the improved ability of the network to generalize across geometrical changes underlying the data using less than 10% of training data and fewer variations of training geometry in comparison to its Euclidean alternatives. In both simulation and real-data experiments, we further demonstrated its ability to be quickly fine-tuned to new geometry using a modest amount of data.

Authors

  • Xiajun Jiang
  • Maryam Toloubidokhti
  • Jake Bergquist
    Department of Biomedical Engineering, University of Utah, SLC, UT, USA.
  • Brian Zenger
    Department of Internal Medicine, Washington University in St Louis, St Louis, MO, USA.
  • Wilson W Good
    Scientific Computing and Imaging Institute, Biomedical Engineering Dept, University of Utah, Salt Lake City, UT, USA.
  • Rob S MacLeod
    Scientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
  • Linwei Wang
    Rochester Institute of Technology, Rochester (NY), USA.