High-Dose Vitamin D Administration Is Associated With Increases in Hemoglobin Concentrations in Mechanically Ventilated Critically Ill Adults: A Pilot Double-Blind, Randomized, Placebo-Controlled Trial.

Journal: JPEN. Journal of parenteral and enteral nutrition
PMID: 29505145

Abstract

BACKGROUND: Anemia and vitamin D deficiency are highly prevalent in critical illness, and vitamin D status has been associated with hemoglobin concentrations in epidemiologic studies. We examined the effect of high-dose vitamin D therapy on hemoglobin and hepcidin concentrations in critically ill adults.

Authors

  • Ellen M Smith
    Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
  • Jennifer L Jones
    Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Jenny E Han
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Jessica A Alvarez
    Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
  • John H Sloan
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Robert J Konrad
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA.
  • Susu M Zughaier
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Greg S Martin
    Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Thomas R Ziegler
    Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
  • Vin Tangpricha
    Nutrition and Health Sciences Program, Laney Graduate School, Emory University, Atlanta, Georgia, USA.

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