A two-stage hybrid biomarker selection method based on ensemble filter and binary differential evolution incorporating binary African vultures optimization.

Journal: BMC bioinformatics
PMID:

Abstract

BACKGROUND: In the field of genomics and personalized medicine, it is a key issue to find biomarkers directly related to the diagnosis of specific diseases from high-throughput gene microarray data. Feature selection technology can discover biomarkers with disease classification information.

Authors

  • Wei Li
    Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
  • Yuhuan Chi
    School of Computer Science and Engineering, Northeastern University, Shenyang, China.
  • Kun Yu
    College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, Liaoning 110819, China.
  • Weidong Xie
    School of Computer Science and Engineering, Northeastern University, Shenyang, China.