Histopathological auxiliary system for brain tumour (HAS-Bt) based on weakly supervised learning using a WHO CNS5-style pipeline.

Journal: Journal of neuro-oncology
Published Date: May 13, 2023

Abstract

PURPOSE: Classification and grading of central nervous system (CNS) tumours play a critical role in the clinic. When WHO CNS5 simplifies the histopathology diagnosis and places greater emphasis on molecular pathology, artificial intelligence (AI) has been widely used to meet the increased need for an automatic histopathology scheme that could liberate pathologists from laborious work. This study was to explore the diagnosis scope and practicality of AI.

Authors

  • Yixin Ma
    Department of Instrument Science and Engineering, School of EIEE, Shanghai Jiao Tong University, Shanghai, China.
  • Feng Shi
    Department of Research and Development, Shanghai United Imaging Intelligence, Co., Ltd. Shanghai, China.
  • Tianyang Sun
    Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
  • Hong Chen
    Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
  • Haixia Cheng
    National Center for Neurological Disorders, Huashan Hospital Fudan University, Shanghai, China.
  • Xiaojia Liu
    National Center for Neurological Disorders, Huashan Hospital Fudan University, Shanghai, China.
  • Shuai Wu
    School of Computer Science and Technology, Henan Polytechnic University, Jiaozuo, Henan, China.
  • Junfeng Lu
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
  • Yaping Zou
    Wuhan Zhongji Biotechnology Co., Ltd, Wuhan, China.
  • Jun Zhang
    First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
  • Lei Jin
    Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States.
  • Dinggang Shen
    School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
  • Jinsong Wu
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.

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