Performance comparison between multi-center histopathology datasets of a weakly-supervised deep learning model for pancreatic ductal adenocarcinoma detection.

Journal: Cancer imaging : the official publication of the International Cancer Imaging Society
Published Date:

Abstract

BACKGROUND: Pancreatic ductal carcinoma patients have a really poor prognosis given its difficult early detection and the lack of early symptoms. Digital pathology is routinely used by pathologists to diagnose the disease. However, visually inspecting the tissue is a time-consuming task, which slows down the diagnostic procedure. With the advances occurred in the area of artificial intelligence, specifically with deep learning models, and the growing availability of public histology data, clinical decision support systems are being created. However, the generalization capabilities of these systems are not always tested, nor the integration of publicly available datasets for pancreatic ductal carcinoma detection (PDAC).

Authors

  • Francisco Carrillo-Perez
    Department of Computer Architecture and Technology, E.T.S.I.I.T.-C.I.T.I.C. University of Granada, Granada, Spain.
  • Francisco M Ortuno
  • Alejandro Börjesson
    Department of Computer Engineering, Automation and Robotics, University of Granada, Granada, Spain.
  • Ignacio Rojas
  • Luis Javier Herrera
    Department of Computer Architecture and Technology, E.T.S.I.I.T.-C.I.T.I.C. University of Granada, Granada, Spain.