AIMC Topic: Carcinoma, Pancreatic Ductal
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Plasma and Urine Circulating Tumor DNA Methylation Profiles for Non-Invasive Pancreatic Ductal Adenocarcinoma Detection: Significant Findings in Plasma Only.
International journal of molecular sciences
May 22, 2025
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options, and early detection remains challenging due to the lack of reliable non-invasive biomarkers. This study investigated plasma and urine circulating tumor deo...
Machine Learning to Predict Early Death Despite Pancreaticoduodenectomy.
The Journal of surgical research
Apr 26, 2025
INTRODUCTION: About 25% of patients undergoing pancreaticoduodenectomy (PD) for right-sided pancreatic ductal adenocarcinoma (PDAC) die within 1 y of diagnosis. These patients carry all the risks of significant morbidity with no survival advantage wh...
Novel CT radiomics models for the postoperative prediction of early recurrence of resectable pancreatic adenocarcinoma: A single-center retrospective study in China.
Journal of applied clinical medical physics
Apr 11, 2025
PURPOSE: To assess the predictive capability of CT radiomics features for early recurrence (ER) of pancreatic ductal adenocarcinoma (PDAC).
Preoperative assessment in lymph node metastasis of pancreatic ductal adenocarcinoma: a transformer model based on dual-energy CT.
World journal of surgical oncology
Apr 9, 2025
BACKGROUND: Deep learning(DL) models can improve significantly discrimination of lymph node metastasis(LNM) of pancreatic ductal adenocarcinoma(PDAC), but have not been systematically assessed.
Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.
International journal of radiation oncology, biology, physics
Apr 2, 2025
PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some p...
Development of PDAC diagnosis and prognosis evaluation models based on machine learning.
BMC cancer
Mar 20, 2025
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and highly aggressive, often leading to poor patient prognosis. Existing serum biomarkers like CA19-9 are limited in early diagnosis, failing to meet clinical needs. Mac...
Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer.
Scientific reports
Mar 19, 2025
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a minority of patients even survives advanced disease for months or years. Thus, there is a clinical ...
A semi-supervised convolutional neural network for diagnosis of pancreatic ductal adenocarcinoma based on EUS-FNA cytological images.
BMC cancer
Mar 18, 2025
BACKGROUND: The cytological diagnostic process of EUS-FNA smears is time-consuming and manpower-intensive, and the conclusion could be subjective and controversial. Moreover, the relative lack of cytopathologists has limited the widespread implementa...
A multimodal framework for assessing the link between pathomics, transcriptomics, and pancreatic cancer mutations.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Mar 15, 2025
In Pancreatic Ductal Adenocarcinoma (PDAC), predicting genetic mutations directly from histopathological images using Deep Learning can provide valuable insights. The combination of several omics can provide further knowledge on mechanisms underlying...
Enhancing pancreatic cancer diagnostics: Ensemble-based model for automated urine biomarker classification.
Computers in biology and medicine
Mar 10, 2025
This research addresses the critical challenge of early detection in pancreatic ductal adenocarcinoma (PDAC) by exploring urinary biomarkers and integrating artificial intelligence (AI) models. The study emphasizes the significance of liquid biopsy, ...
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