AIMC Topic: Pancreatic Neoplasms
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Unveiling the mechanisms and promising molecular targets of curcumin in pancreatic cancer through multi-dimensional data.
Scientific reports
Jul 1, 2025
Pancreatic cancer (PC) is a highly aggressive and fatal malignancy, primarily affecting older males. Curcumin, a potential anti-cancer agent, has been shown to regulate key molecules in cancer progression, but its specific mechanisms in PC remain unc...
Harnessing artificial intelligence for detection of pancreatic cancer: a machine learning approach.
Clinical and experimental medicine
Jul 1, 2025
PURPOSE: Pancreatic cancer (PC) is one of the most lethal malignancies, often presenting with nonspecific symptoms and a dismal prognosis. Despite advancements in treatments, the 5-year survival rate remains low, highlighting the urgent need for effe...
Enhancing pancreatic cancer detection in CT images through secretary wolf bird optimization and deep learning.
Scientific reports
Jun 5, 2025
The pancreas is a gland in the abdomen that helps to produce hormones and digest food. The irregular development of tissues in the pancreas is termed as pancreatic cancer. Identification of pancreatic tumors early is significant for enhancing surviva...
Toward diffusion MRI in the diagnosis and treatment of pancreatic cancer.
Medical oncology (Northwood, London, England)
May 28, 2025
Pancreatic cancer is a highly aggressive malignancy with rising incidence and mortality rates, often diagnosed at advanced stages. Conventional imaging methods, such as computed tomography (CT) and magnetic resonance imaging (MRI), struggle to assess...
Innate immune cell barrier-related genes inform precision prognosis in pancreatic cancer.
Frontiers in immunology
May 23, 2025
INTRODUCTION: Pancreatic cancer (PC) remains a lethal malignancy with limited treatment options. The role of innate immune cell barrier-related genes in PC prognosis is poorly defined. This study aimed to identify prognostic biomarkers, develop a pre...
Plasma and Urine Circulating Tumor DNA Methylation Profiles for Non-Invasive Pancreatic Ductal Adenocarcinoma Detection: Significant Findings in Plasma Only.
International journal of molecular sciences
May 22, 2025
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options, and early detection remains challenging due to the lack of reliable non-invasive biomarkers. This study investigated plasma and urine circulating tumor deo...
Pancreas segmentation using AI developed on the largest CT dataset with multi-institutional validation and implications for early cancer detection.
Scientific reports
May 16, 2025
Accurate and fully automated pancreas segmentation is critical for advancing imaging biomarkers in early pancreatic cancer detection and for biomarker discovery in endocrine and exocrine pancreatic diseases. We developed and evaluated a deep learning...
High-Precision Intelligent Diagnosis of Pancreatic Cancer: Flowing Diffuseness from Single to Whole.
Analytical chemistry
Apr 29, 2025
Raman spectroscopy, as a label-free optical technique, provides a unique solution for tissue diagnosis. However, due to the limitation of point-by-point acquisition mode and multivariate statistical analysis methods, conventional methods pose a major...
Machine Learning-Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi-Omics.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Apr 28, 2025
The malignant potential of pancreatic cystic lesions (PCLs) varies dramatically, leading to difficulties when making clinical decisions. This study aimed to develop noninvasive clinical-radiomic models using preoperative CT images to predict the mali...
Machine Learning to Predict Early Death Despite Pancreaticoduodenectomy.
The Journal of surgical research
Apr 26, 2025
INTRODUCTION: About 25% of patients undergoing pancreaticoduodenectomy (PD) for right-sided pancreatic ductal adenocarcinoma (PDAC) die within 1 y of diagnosis. These patients carry all the risks of significant morbidity with no survival advantage wh...
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