Exploring the challenge of early gastric cancer diagnostic AI system face in multiple centers and its potential solutions.

Journal: Journal of gastroenterology
Published Date:

Abstract

BACKGROUND: Artificial intelligence (AI) performed variously among test sets with different diversity due to sample selection bias, which can be stumbling block for AI applications. We previously tested AI named ENDOANGEL, diagnosing early gastric cancer (EGC) on single-center videos in man-machine competition. We aimed to re-test ENDOANGEL on multi-center videos to explore challenges applying AI in multiple centers, then upgrade ENDOANGEL and explore solutions to the challenge.

Authors

  • Zehua Dong
    Department of Internal Medicine, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, Hubei Province, China.
  • Xiao Tao
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Hongliu Du
    Department of Gastroenterology, Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, and Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China.
  • Junxiao Wang
    School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing 210023, China. dz1427034@smail.nju.edu.cn.
  • Li Huang
    National Research Center for Resettlement (NRCR), Hohai University, 1 Xikang Road, Nanjing 210098, China. lily8214@hhu.edu.cn.
  • Chiyi He
    Department of Gastroenterology, Yijishan Hospital of Wannan Medical College, Wuhu, 241001, Anhui, People's Republic of China.
  • Zhifeng Zhao
    College of Biomass Science and Engineering, Healthy Food Evaluation Research Center, Sichuan University, Chengdu 610065, China.
  • Xinli Mao
    Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, China.
  • Yaowei Ai
    Department of Gastroenterology, The People's Hospital of China Three Gorges University, The First People's Hospital of Yichang, Yichang, China.
  • Beiping Zhang
    Department of Gastroenterology, Guangdong Province Traditional Chinese Medical Hospital, Guangzhou, China.
  • Mei Liu
    Department of Internal Medicine, Division of Medical Informatics, University of Kansas Medical Center, Kansas City, Missouri, USA.
  • Hong Xu
    Department of Neurosurgery, Changshu Hospital Affiliated to Soochow University, Changshu, China.
  • Zhenyu Jiang
    Department of Electronic Engineering, Tsinghua University, Beijing, 100084, China.
  • Yunwei Sun
    Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University, Gubei Branch, Shanghai, People's Republic of China.
  • Xiuling Li
    Department of Gastroenterology, School of Clinical Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Henan University, Zhengzhou, Henan, China.
  • Zhihong Liu
    National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
  • Jinzhong Chen
    Endoscopy Center, School of Medicine, The First Affiliated Hospital of Xiamen University, Xiamen University, Xiamen, China.
  • Ying Song
    Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Guowei Liu
    Yi Xin Clinic, Changzhou, Jiangsu, China.
  • Chaijie Luo
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Yanxia Li
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Xiaoquan Zeng
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Jun Liu
    Department of Radiology, Second Xiangya Hospital, Changsha, Hunan, China.
  • Yijie Zhu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China.
  • Lianlian Wu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
  • Honggang Yu
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.