Gastric cancer (GC) remains a significant global health challenge with high mortality rates, often due to late-stage diagnosis. We hypothesize that Raman spectroscopy (RS) (a modern minimally invasive technique that uses light to analyze the molecula...
AIMS: Accurate cancer subtype classification is critical due to variations in tumor progression and prognosis. Traditionally, pathologists classified subtypes manually by examining pathological slides under the microscope. To address increasing workl...
BACKGROUND: The development of immunotherapy has provided new hope for patients with advanced gastric cancer (AGC). However, due to the high heterogeneity of the disease, the efficacy of first-line immunochemotherapy varies among patients. There is s...
Biochemical and biophysical research communications
Dec 17, 2025
The dry fruits of Amomum villosum (Av) are a traditional Chinese medicine used for gastrointestinal disease. Aromatic oil has been reported to have anti-tumor properties. However, its therapeutic potential and molecular mechanisms remain unclear. Int...
Gastric cancer (GC) is a leading cause of cancer-related mortality globally. Histone lactylation, an emerging post-translational modification, holds promise as a therapeutic target and prognostic biomarker, though its expression patterns and clinical...
Univariate and multivariate Cox analyses revealed a correlation between diabetes and the prognosis of gastric cancer patients (p < 0.05). Using bioinformatics, Serine/threonine-protein kinase pim-1 (PIM1) was identified as the core target gene of tri...
BACKGROUND: Machine learning has emerged as a promising tool for survival prediction in various diseases; however, its application and external validation in real-world gastric cancer populations remain limited.
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...
Gastric cancer (GC) presents striking survival disparities: 85-100% for early-stage versus only 5-20% for advanced disease. Glucose metabolic reprogramming (GMS)-a cancer hallmark linked to the Warburg effect-fuels tumor progression and immune evasio...
Automatic segmentation of gastric lesions in ultrasound images is crucial for the early diagnosis and treatment of gastric cancer, the second leading cause of cancer-related deaths worldwide. However, the limited amount of related research and the ch...
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