Recent progress in transformer-based medical image analysis.

Journal: Computers in biology and medicine
Published Date:

Abstract

The transformer is primarily used in the field of natural language processing. Recently, it has been adopted and shows promise in the computer vision (CV) field. Medical image analysis (MIA), as a critical branch of CV, also greatly benefits from this state-of-the-art technique. In this review, we first recap the core component of the transformer, the attention mechanism, and the detailed structures of the transformer. After that, we depict the recent progress of the transformer in the field of MIA. We organize the applications in a sequence of different tasks, including classification, segmentation, captioning, registration, detection, enhancement, localization, and synthesis. The mainstream classification and segmentation tasks are further divided into eleven medical image modalities. A large number of experiments studied in this review illustrate that the transformer-based method outperforms existing methods through comparisons with multiple evaluation metrics. Finally, we discuss the open challenges and future opportunities in this field. This task-modality review with the latest contents, detailed information, and comprehensive comparison may greatly benefit the broad MIA community.

Authors

  • Zhaoshan Liu
    School of Economics and Management, Taishan University, Taian 271000, Shandong, China.
  • Qiujie Lv
    School of Intelligent Systems Engineering, Sun Yat-sen University, Shenzhen, 510275, China.
  • Ziduo Yang
    Artificial Intelligence Medical Center, School of Intelligent Systems Engineering, Sun Yat-sen University, Shenzhen 510275, China.
  • Yifan Li
    College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA.
  • Chau Hung Lee
    Department of Radiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. Electronic address: chau_hung_lee@ttsh.com.sg.
  • Lei Shen
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.