Machine Learning Classification of Body Part, Imaging Axis, and Intravenous Contrast Enhancement on CT Imaging.

Journal: Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
Published Date:

Abstract

The development and evaluation of machine learning models that automatically identify the body part(s) imaged, axis of imaging, and the presence of intravenous contrast material of a CT series of images. This retrospective study included 6955 series from 1198 studies (501 female, 697 males, mean age 56.5 years) obtained between January 2010 and September 2021. Each series was annotated by a trained board-certified radiologist with labels consisting of 16 body parts, 3 imaging axes, and whether an intravenous contrast agent was used. The studies were randomly assigned to the training, validation and testing sets with a proportion of 70%, 20% and 10%, respectively, to develop a 3D deep neural network for each classification task. External validation was conducted with a total of 35,272 series from 7 publicly available datasets. The classification accuracy for each series was independently assessed for each task to evaluate model performance. The accuracies for identifying the body parts, imaging axes, and the presence of intravenous contrast were 96.0% (95% CI: 94.6%, 97.2%), 99.2% (95% CI: 98.5%, 99.7%), and 97.5% (95% CI: 96.4%, 98.5%) respectively. The generalizability of the models was demonstrated through external validation with accuracies of 89.7 - 97.8%, 98.6 - 100%, and 87.8 - 98.6% for the same tasks. The developed models demonstrated high performance on both internal and external testing in identifying key aspects of a CT series.

Authors

  • Wuqi Li
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada.
  • Hui Ming Lin
    Department of Medical Imaging, St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
  • Amy Lin
    University of Illinois Hospital and Health Sciences System, Chicago, IL, USA.
  • Marc Napoleone
    Department of Medical Imaging, Unity Health Toronto, Toronto, ON, Canada.
  • Robert Moreland
    Department of Medical Imaging, St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
  • Alexis Murari
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada.
  • Maxim Stepanov
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada.
  • Eric Ivanov
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada.
  • Abhinav Sanjeeva Prasad
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada.
  • George Shih
  • Zixuan Hu
    The Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, Canada.
  • Suvd Zulbayar
    Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
  • Ervin Sejdić
    Department of Electrical and Computer Engineering, University of Pittsburgh, Benedum Hall, Pittsburgh, PA 15260, USA. Electronic address: esejdic@ieee.org.
  • Errol Colak
    Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.