Simultaneous Quantitative Analysis of Salmeterol and Fluticasone in Inhalation Spray Using HPLC and a Fast Spectrophotometric Technique Combined with a Time Series Neural Network and Multivariate Calibration Methods.

Journal: Journal of AOAC International
PMID: 36715079

Abstract

BACKGROUND: Chromatographic methods have been used for the simultaneous determination of salmeterol (SMT) and fluticasone (FLU). The methods take a lot of analysis time, need sample pre-treatment and large amounts of solvents, and are costly.

Authors

  • Maryam Valizadeh
    Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran.
  • Zahra Ameri Braki
    Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran.
  • Erfan Smiley
    Islamic Azad University, Department of Chemistry, North Tehran Branch, Vafadar Blvd., Shahid Sadoughi St., Hakimiyeh Exit, Shahid Babaee Highway, Tehran 1651153311, Iran.
  • Arezoo Arghand
    Islamic Azad University, Department of Chemistry, North Tehran Branch, Vafadar Blvd., Shahid Sadoughi St., Hakimiyeh Exit, Shahid Babaee Highway, Tehran 1651153311, Iran.
  • Poriya Dastafkan
    Islamic Azad University, Faculty of Sciences, Department of Chemistry, Rasht Branch, Rasht 4147654919, Iran.

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