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Spectrophotometry

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Simultaneous spectrophotometric quantitative analysis of velpatasvir and sofosbuvir in recently approved FDA pharmaceutical preparation using artificial neural networks and genetic algorithm artificial neural networks.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Two chemometric assisted spectrophotometric models were applied for the quantitative analysis of velpatasvir and sofosbuvir in their newly FDA approved pharmaceutical dosage form. The UV absorption spectra of velpatasvir and sofosbuvir showed certain...

Investigation of spectrophotometric simultaneous absorption of Salmeterol and Fluticasone in Seroflo spray by continuous wavelet transform and radial basis function neural network methods.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In this research, the simultaneous absorption of Salmeterol (SAL) and Fluticasone (FLU) in Seroflo spray was investigated using a spectrophotometric device via employing continuous wavelet transform (CWT) and radial basis function neural network (RBF...

Chemometric quality assessment of Paracetamol and Phenylephrine Hydrochloride with Paracetamol impurities; comparative UV-spectrophotometric implementation of four predictive models.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Spectrophotometric data analysis using multivariate approaches has many useful applications. One of these applications is the analysis of active ingredients in presence of impurities. Four chemometric-assisted spectrophotometric methods, namely, prin...

Nature inspired computation and ensemble neural network to build a robust model for spectral data.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
UV spectrophotometry was introduced for simultaneous determination of Itraconazole (ITZ) and Secnidazole (SEZ) in their mixture without any prior separation. In this study, fourteen nature-inspired algorithms combined with partial least squares (PLS)...

Rapid simultaneous analysis of anti human immunodeficiency virus drugs in pharmaceutical formulation by smart spectrophotometry based on multivariate calibration and least squares support vector machine methods.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In this study, two chemometrics methods, including partial least squares regression (PLS) and least squares support vector machine (LS-SVM) were applied for the simultaneous determination of zidovudine (ZDV) and lamivudine (LMV) in synthetic mixtures...

Simultaneous Quantitative Analysis of Salmeterol and Fluticasone in Inhalation Spray Using HPLC and a Fast Spectrophotometric Technique Combined with a Time Series Neural Network and Multivariate Calibration Methods.

Journal of AOAC International
BACKGROUND: Chromatographic methods have been used for the simultaneous determination of salmeterol (SMT) and fluticasone (FLU). The methods take a lot of analysis time, need sample pre-treatment and large amounts of solvents, and are costly.

A machine learning approach for rapid early detection of Campylobacter spp. using absorbance spectra collected from enrichment cultures.

PloS one
Enumeration of Campylobacter from environmental waters can be difficult due to its low concentrations, which can still pose a significant health risk. Spectrophotometry is an approach commonly used for fast detection of water-borne pollutants in wate...

Simultaneous Determination of Estradiol Cypionate and Medroxyprogesterone Acetate Hormones in Injectable Suspension by UV Spectrophotometry Based on Least-Squares Support Vector Machine and Fuzzy Inference System: Comparison with HPLC.

Journal of AOAC International
BACKGROUND: The combination of estradiol cypionate (ECA) and medroxyprogesterone acetate (MPA) is used to prevent pregnancy in women. The analysis of the ECA and MPA combination reveals a challenge due to the strong overlap of the spectra of these co...

Lesion segmentation using 3D scan and deep learning for the evaluation of facial portwine stain birthmarks.

Photodiagnosis and photodynamic therapy
BACKGROUND: Portwine stain (PWS) birthmarks are congenital vascular malformations. The quantification of PWS area is an important step in lesion classification and treatment evaluation.

Non-invasive prediction of maca powder adulteration using a pocket-sized spectrophotometer and machine learning techniques.

Scientific reports
Discriminating different cultivars of maca powder (MP) and detecting their authenticity after adulteration with potent adulterants such as maize and soy flour is a challenge that has not been studied with non-invasive techniques such as near infrared...