Combining radiomics and deep learning features of intra-tumoral and peri-tumoral regions for the classification of breast cancer lung metastasis and primary lung cancer with low-dose CT.

Journal: Journal of cancer research and clinical oncology
Published Date:

Abstract

PURPOSE: To investigate the performance of deep learning and radiomics features of intra-tumoral region (ITR) and peri-tumoral region (PTR) in the diagnosing of breast cancer lung metastasis (BCLM) and primary lung cancer (PLC) with low-dose CT (LDCT).

Authors

  • Lei Li
    Department of Thoracic Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huai'an, China.
  • Xinglu Zhou
    Department of PET/CT Center, Harbin Medical University Cancer Hospital, Harbin, 150081, China.
  • Wenju Cui
    School of Biomedical Engineering (Suzhou), University of Science and Technology of China, Division of Life Sciences and Medicine, Hefei, 230026, Anhui, China.
  • Yingci Li
    Center of PET/CT, The Third Affiliated Hospital of Harbin Medical University, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, China.
  • Tianyi Liu
    Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China.
  • Gang Yuan
    School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230022, China; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, China. Electronic address: yuangang@sibet.ac.cn.
  • Yunsong Peng
  • Jian Zheng
    Biospheric Assessment for Waste Disposal Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan; Fukushima Project Headquarters, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan. Electronic address: zheng.jian@qst.go.jp.