Chest radiography as a biomarker of ageing: artificial intelligence-based, multi-institutional model development and validation in Japan.

Journal: The lancet. Healthy longevity
Published Date: Aug 16, 2023

Abstract

BACKGROUND: Chest radiographs are widely available and cost-effective; however, their usefulness as a biomarker of ageing using multi-institutional data remains underexplored. The aim of this study was to develop a biomarker of ageing from chest radiography and examine the correlation between the biomarker and diseases.

Authors

  • Yasuhito Mitsuyama
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Toshimasa Matsumoto
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-ku, Osaka, 545-8585, Japan.
  • Hiroyuki Tatekawa
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Shannon L Walston
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Tatsuo Kimura
    Department of Premier Preventive Medicine, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
  • Akira Yamamoto
    From the Department of Diagnostic and Interventional Radiology (D.U., A.Y., T.S., S.D., A.S., Y.M.) and Department of Premier Preventive Medicine (S.F.), Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan; LPixel, Tokyo, Japan (M.N., A.C., Y.S.); and Department of Radiology, Osaka City University Hospital, Osaka, Japan (Y.K.).
  • Toshio Watanabe
    Department of Premier Preventive Medicine, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
  • Yukio Miki
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Daiju Ueda
    Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. ai.labo.ocu@gmail.com.

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