Developing and deploying deep learning models in brain magnetic resonance imaging: A review.

Journal: NMR in biomedicine
Published Date:

Abstract

Magnetic resonance imaging (MRI) of the brain has benefited from deep learning (DL) to alleviate the burden on radiologists and MR technologists, and improve throughput. The easy accessibility of DL tools has resulted in a rapid increase of DL models and subsequent peer-reviewed publications. However, the rate of deployment in clinical settings is low. Therefore, this review attempts to bring together the ideas from data collection to deployment in the clinic, building on the guidelines and principles that accreditation agencies have espoused. We introduce the need for and the role of DL to deliver accessible MRI. This is followed by a brief review of DL examples in the context of neuropathologies. Based on these studies and others, we collate the prerequisites to develop and deploy DL models for brain MRI. We then delve into the guiding principles to develop good machine learning practices in the context of neuroimaging, with a focus on explainability. A checklist based on the United States Food and Drug Administration's good machine learning practices is provided as a summary of these guidelines. Finally, we review the current challenges and future opportunities in DL for brain MRI.

Authors

  • Kunal Aggarwal
    Centre of Excellence for Translational Research in Asthma & Lung Disease, CSIR-Institute of Genomics and Integrated Biology, Mall Road, Delhi, 110007, India.
  • Marina Manso Jimeno
    Department of Biomedical Engineering, Columbia University in the City of New York, New York, NY 10027, USA; Columbia University Magnetic Resonance Research Center, Columbia University in the City of New York, New York, NY 10027, USA.
  • Keerthi Sravan Ravi
    Department of Biomedical Engineering, Columbia University in the City of New York, New York, NY 10027, USA; Columbia University Magnetic Resonance Research Center, Columbia University in the City of New York, New York, NY 10027, USA.
  • Gilberto Gonzalez
    Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Sairam Geethanath
    Columbia University Magnetic Resonance Research Center, Columbia University in the City of New York, New York, NY 10027, USA. Electronic address: sg3606@columbia.edu.