DeepTraSynergy: drug combinations using multimodal deep learning with transformers.

Journal: Bioinformatics (Oxford, England)
Published Date: Aug 1, 2023

Abstract

MOTIVATION: Screening bioactive compounds in cancer cell lines receive more attention. Multidisciplinary drugs or drug combinations have a more effective role in treatments and selectively inhibit the growth of cancer cells.

Authors

  • Fatemeh Rafiei
    Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
  • Hojjat Zeraati
    Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran 1417613151, Iran.
  • Karim Abbasi
    Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran, Tehran 1417614411, Iran.
  • Jahan B Ghasemi
    Drug Design in Silico Lab., Chemistry Faculty, University of Tehran, Tehran, Iran.
  • Mahboubeh Parsaeian
    Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, P.O. Box 14155-6446, Tehran, Iran. mahbobehparsaeian@yahoo.com.
  • Ali Masoudi-Nejad
    Laboratory of system Biology and Bioinformatics, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran. amasoudin@ut.ac.ir.

Keywords

External Resources

Popular Topics
Recent Journals