Adaptive machine learning method for photoacoustic computed tomography based on sparse array sensor data.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: Photoacoustic computed tomography (PACT) is a non-invasive biomedical imaging technology that has developed rapidly in recent decades, especially has shown potential for small animal studies and early diagnosis of human diseases. To obtain high-quality images, the photoacoustic imaging system needs a high-element-density detector array. However, in practical applications, due to the cost limitation, manufacturing technology, and the system requirement in miniaturization and robustness, it is challenging to achieve sufficient elements and high-quality reconstructed images, which may even suffer from artifacts. Different from the latest machine learning methods based on removing distortions and artifacts to recover high-quality images, this paper proposes an adaptive machine learning method to firstly predict and complement the photoacoustic sensor channel data from sparse array sampling and then reconstruct images through conventional reconstruction algorithms.

Authors

  • Ruofan Wang
    School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072, China.
  • Jing Zhu
    College of Environmental Science and Engineering, Beijing Forestry University, Beijing 100083, China.
  • Yuqian Meng
    Zhejiang Lab, Hangzhou 311100, China.
  • Xuanhao Wang
    Zhejiang Lab, Hangzhou 311100, China.
  • Ruimin Chen
    Zhejiang Lab, Hangzhou 311100, China.
  • Kaiyue Wang
    Zhejiang Lab, Hangzhou 311100, China.
  • Chiye Li
    Zhejiang Lab, Hangzhou 311100, China; Research Center for Humanoid Sensing, Zhejiang Lab, Hangzhou 311100, China. Electronic address: chiye.li@zhejianglab.com.
  • Junhui Shi
    Zhejiang Lab, Hangzhou 311100, China; Research Center for Humanoid Sensing, Zhejiang Lab, Hangzhou 311100, China. Electronic address: junhuishi@zhejianglab.com.