Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach: The AI-VascularAge Model.

Journal: Hypertension (Dallas, Tex. : 1979)
PMID:

Abstract

BACKGROUND: Aortic stiffness, assessed as carotid-femoral pulse wave velocity, provides a measure of vascular age and risk for adverse cardiovascular disease outcomes, but it is difficult to measure. The shape of arterial pressure waveforms conveys information regarding aortic stiffness; however, the best methods to extract and interpret waveform features remain controversial.

Authors

  • Gary F Mitchell
    Cardiovascular Engineering, Inc, Norwood, MA (G.F.M., T.J.K., J.D.G.).
  • Jian Rong
    Boston University and NHLBI's Framingham Study, MA (J.R., M.G.L., V.X., R.S.V.).
  • Martin G Larson
    Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
  • Timothy J Korzinski
    Cardiovascular Engineering, Inc, Norwood, MA (G.F.M., T.J.K., J.D.G.).
  • Vanessa Xanthakis
    Boston University and NHLBI's Framingham Study, MA (J.R., M.G.L., V.X., R.S.V.).
  • Sigurdur Sigurdsson
    The Icelandic Heart Association, Kopavogur, Iceland.
  • Vilmundur Gudnason
    Department of Medicine, University of Iceland, Reykjavik, Iceland; The Icelandic Heart Association, Kopavogur, Iceland.
  • Lenore J Launer
    Neuroepidemiology Section, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.
  • Thor Aspelund
    Icelandic Heart Association, Kópavogur (S.S., V.G., T.A.).
  • Naomi M Hamburg
    Evans Department of Medicine and Whitaker Cardiovascular Institute, Boston University Chobanian & Avedisian School of Medicine, MA (N.M.H., R.S.V.).
  • John D Gotal
    Cardiovascular Engineering, Inc, Norwood, MA (G.F.M., T.J.K., J.D.G.).
  • Ramachandran S Vasan
    Framingham Heart Study, Framingham, Massachusetts.