Detecting changes in the performance of a clinical machine learning tool over time.

Journal: EBioMedicine
Published Date:

Abstract

BACKGROUND: Excessive use of blood cultures (BCs) in Emergency Departments (EDs) results in low yields and high contamination rates, associated with increased antibiotic use and unnecessary diagnostics. Our team previously developed and validated a machine learning model to predict BC outcomes and enhance diagnostic stewardship. While the model showed promising initial results, concerns over performance drift due to evolving patient demographics, clinical practices, and outcome rates warrant continual monitoring and evaluation of such models.

Authors

  • Michiel Schinkel
  • Anneroos W Boerman
    Department of Internal Medicine, Section General Internal Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.
  • Ketan Paranjape
  • W Joost Wiersinga
    Center for Experimental and Molecular Medicine and.
  • Prabath W B Nanayakkara
    Department of Internal Medicine, Section General Internal Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.