Simultaneous object detection and segmentation for patient-specific markerless lung tumor tracking in simulated radiographs with deep learning.

Journal: Medical physics
Published Date:

Abstract

BACKGROUND: Real-time tumor tracking is one motion management method to address motion-induced uncertainty. To date, fiducial markers are often required to reliably track lung tumors with X-ray imaging, which carries risks of complications and leads to prolonged treatment time. A markerless tracking approach is thus desirable. Deep learning-based approaches have shown promise for markerless tracking, but systematic evaluation and procedures to investigate applicability in individual cases are missing. Moreover, few efforts have been made to provide bounding box prediction and mask segmentation simultaneously, which could allow either rigid or deformable multi-leaf collimator tracking.

Authors

  • Lili Huang
    Department of Endocrinology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.
  • Christopher Kurz
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München (LMU Munich), Garching bei München, 85748, Germany.
  • Philipp Freislederer
    Department of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
  • Farkhad Manapov
    Department of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
  • Stefanie Corradini
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Maximilian Niyazi
    Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany.
  • Claus Belka
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Guillaume Landry
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München (LMU Munich), Garching bei München, 85748, Germany.
  • Marco Riboldi
    Department of Medical Physics, Ludwig-Maximilians-Universität München, Germany.