[Not Available].

Journal: Recenti progressi in medicina
Published Date:

Abstract

Advancing our understanding of complex diseases necessitates an interdisciplinary dialogue beyond artificial intelligence (AI) in the field of medicine. Two decades after the completion of the Human Genome Project, genetic sequencing has facilitated targeted therapies for gene mutation-related ailments. However, this achievement has unveiled the immense gaps in our comprehension of life and disease mechanisms. Complex diseases, including cancer, diabetes, and autoimmune disorders, remain elusive due to their multifactorial nature. Consequently, a more holistic approach integrating AI with diverse scientific disciplines becomes imperative. This paper emphasizes the urgency of fostering collaboration among genetics, molecular biology, computational biology, and clinical research to unravel the intricate complexities underlying these diseases. By synergizing expertise and data from various domains, we can make significant strides towards unraveling the intricate web of complex diseases, leading to improved diagnosis, treatment, and ultimately, patient outcomes.

Authors

  • Marco Filetti
    Uoc Fase 1, Fondazione Policlinico universitario Agostino Gemelli, Irccs, Roma - Dipartimento di Medicina sperimentale, Sapienza Università di Roma - Ph.D. Program in "Network oncology and precision medicine", Sapienza Università di Roma.
  • Manuela Petti
    Dipartimento di Ingegneria informatica, automatica e gestionale "Antonio Ruberti", Sapienza Università di Roma - Ph.D. Program in "Network oncology and precision medicine", Sapienza Università di Roma.
  • Lorenzo Farina
    Dipartimento di Ingegneria informatica, automatica e gestionale "Antonio Ruberti", Sapienza Università di Roma - Ph.D. Program in "Network oncology and precision medicine", Sapienza Università di Roma.