Tumor classification of gastrointestinal liver metastases using CT-based radiomics and deep learning.

Journal: Cancer imaging : the official publication of the International Cancer Imaging Society
Published Date:

Abstract

OBJECTIVES: The goal of this study is to demonstrate the performance of radiomics and CNN-based classifiers in determining the primary origin of gastrointestinal liver metastases for visually indistinguishable lesions.

Authors

  • Hishan Tharmaseelan
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Abhinay K Vellala
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Alexander Hertel
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Fabian Tollens
    Klinik für Radiologie und Nuklearmedizin, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
  • Lukas T Rotkopf
    Department of Radiology, German Cancer Research Centre, Heidelberg, Germany.
  • Johann Rink
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Piotr Woźnicki
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Isabelle Ayx
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Sönke Bartling
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
  • Dominik Norenberg
  • Stefan O Schoenberg
    University Medical Center Mannheim, Faculty of Medicine Mannheim, Institute of Clinical Radiology and Nuclear Medicine, Heidelberg University, Mannheim, Germany.
  • Matthias F Froelich
    Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. matthias.froelich@medma.uni-heidelberg.de.