Feasibility interventional study investigating PAIN in neurorehabilitation through wearabLE SensorS (PAINLESS): a study protocol.

Journal: BMJ open
PMID:

Abstract

INTRODUCTION: Millions of people survive injuries to the central or peripheral nervous system for which neurorehabilitation is required. In addition to the physical and cognitive impairments, many neurorehabilitation patients experience pain, often not widely recognised and inadequately treated. This is particularly true for multiple sclerosis (MS) patients, for whom pain is one of the most common symptoms. In clinical practice, pain assessment is usually conducted based on a subjective estimate. This approach can lead to inaccurate evaluations due to the influence of numerous factors, including emotional or cognitive aspects. To date, no objective and simple to use clinical methods allow objective quantification of pain and the diagnostic differentiation between the two main types of pain (nociceptive vs neuropathic). Wearable technologies and artificial intelligence (AI) have the potential to bridge this gap by continuously monitoring patients' health parameters and extracting meaningful information from them. Therefore, we propose to develop a new automatic AI-powered tool to assess pain and its characteristics during neurorehabilitation treatments using physiological signals collected by wearable sensors.

Authors

  • Serena Moscato
    Department of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" - DEI, Alma Mater Studiorum University of Bologna, Bologna, Italy.
  • Silvia Orlandi
    Department of Information Engineering, Università degli Studi di Firenze, Via di S. Marta 3, 50139 Firenze, Italy. Electronic address: silvia.orlandi@unifi.it.
  • Francesco Di Gregorio
    UOC Medicina Riabilitativa e Neuroriabilitazione, Azienda Unità Sanitaria Locale di Bologna, Bologna, Italy.
  • Giada Lullini
    IRCCS Istituto delle Scienze Neurologuche di Bologna, Bologna, Italy.
  • Stefania Pozzi
    DATER Riabilitazione Ospedaliera, UA Riabilitazione, Azienda Unità Sanitaria Locale di Bologna, Bologna, Italy.
  • Loredana Sabattini
    IRCCS Istituto delle Scienze Neurologuche di Bologna, Bologna, Italy.
  • Lorenzo Chiari
    Department of Electrical, Electronic and Information Engineering "Guglielmo Marconi, " University of Bologna, Bologna, Italy.
  • Fabio La Porta
    IRCCS Istituto delle Scienze Neurologuche di Bologna, Bologna, Italy fabiolaporta@mail.com.