A deep learning system for detection of early Barrett's neoplasia: a model development and validation study.

Journal: The Lancet. Digital health
PMID:

Abstract

BACKGROUND: Computer-aided detection (CADe) systems could assist endoscopists in detecting early neoplasia in Barrett's oesophagus, which could be difficult to detect in endoscopic images. The aim of this study was to develop, test, and benchmark a CADe system for early neoplasia in Barrett's oesophagus.

Authors

  • K N Fockens
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • M R Jong
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • J B Jukema
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • T G W Boers
    Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
  • C H J Kusters
    Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
  • J A van der Putten
    Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
  • R E Pouw
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • L C Duits
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • N S M Montazeri
    Biostatistics Unit, Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
  • S N van Munster
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, Netherlands.
  • B L A M Weusten
    Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • L Alvarez Herrero
    Department of Gastroenterology and Hepatology, St Antonius Hospital, Nieuwegein, Netherlands.
  • M H M G Houben
    Department of Gastroenterology and Hepatology, HagaZiekenhuis Den Haag, Den Haag, Netherlands.
  • W B Nagengast
    Department of Gastroenterology and Hepatology, UMC Groningen, University of Groningen, Groningen, Netherlands.
  • J Westerhof
    Department of Gastroenterology and Hepatology, UMC Groningen, University of Groningen, Groningen, Netherlands.
  • A Alkhalaf
    Department of Gastroenterology and Hepatology, Isala Hospital Zwolle, Zwolle, Netherlands.
  • R C Mallant-Hent
    Department of Gastroenterology and Hepatology, Flevoziekenhuis Almere, Almere, Netherlands.
  • P Scholten
    Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands.
  • K Ragunath
    Department of Gastroenterology and Hepatology, Royal Perth Hospital, Curtin University, Perth, WA, Australia.
  • S Seewald
    Department of Gastroenterology and Hepatology, Hirslanden Klinik, Zurich, Switzerland.
  • P Elbe
    Department of Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
  • F Baldaque-Silva
    Department of Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Center for Advanced Endoscopy Carlos Moreira da Silva, Gastroenterology Department, Pedro Hispano Hospital, Matosinhos, Portugal.
  • M Barret
    Department of Gastroenterology and Hepatology, Cochin Hospital Paris, Paris, France.
  • J Ortiz Fernández-Sordo
    Department of Gastroenterology and Hepatology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
  • G Moral Villarejo
    Department of Gastroenterology and Hepatology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
  • O Pech
    Department of Gastroenterology and Hepatology, St John of God Hospital, Regensburg, Germany.
  • T Beyna
    Department of Gastroenterology and Hepatology, Evangalisches Krankenhaus Düsseldorf, Düsseldorf, Germany.
  • F van der Sommen
    Department of Electrical Engineering, Eindhoven University of Technology, Groene Loper 19, 5612 AP, Eindhoven, The Netherlands.
  • P H de With
    Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
  • A J de Groof
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: a.j.degroof@amsterdamumc.nl.
  • J J Bergman
    Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. Electronic address: j.j.bergman@amsterdamumc.nl.