CheRRI-Accurate classification of the biological relevance of putative RNA-RNA interaction sites.

Journal: GigaScience
Published Date: Jan 2, 2024

Abstract

BACKGROUND: RNA-RNA interactions are key to a wide range of cellular functions. The detection of potential interactions helps to understand the underlying processes. However, potential interactions identified via in silico or experimental high-throughput methods can lack precision because of a high false-positive rate.

Authors

  • Teresa Müller
    Bioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.
  • Stefan Mautner
    Bioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.
  • Pavankumar Videm
    Bioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.
  • Florian Eggenhofer
    Bioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.
  • Martin Raden
    Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany.
  • Rolf Backofen
    Bioinformatics Group, Department of Computer Science, Albert-Ludwigs-University Freiburg, Georges-Köhler-Allee 106, Freiburg, 79110, Germany.

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