Predicting 5-year recurrence risk in colorectal cancer: development and validation of a histology-based deep learning approach.

Journal: British journal of cancer
Published Date:

Abstract

BACKGROUND: Accurate estimation of the long-term risk of recurrence in patients with non-metastatic colorectal cancer (CRC) is crucial for clinical management. Histology-based deep learning is expected to provide more abundant information for risk stratification.

Authors

  • Han Xiao
    Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Zongpeng Weng
    Clinical Trials Unit, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Kaiyu Sun
    Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Jingxian Shen
    Department of Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China.
  • Jie Lin
    Department of Reproductive Medicine, Zigong Hospital of Women and Children Health Care, Zigong, China.
  • Shuling Chen
    Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. chenshling@mail.sysu.edu.cn.
  • Bin Li
    Department of Magnetic Resonance Imaging (MRI), Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Yiyu Shi
    University of Notre Dame.
  • Ming Kuang
    School of Medicine, Jiangsu University, Zhenjiang 212013, China.
  • Xinming Song
    Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Weixiang Weng
    Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. wengwx3@mail2.sysu.edu.cn.
  • Sui Peng
    Center for Precision Medicine, Sun Yat-sen University, Guangzhou, 510080, China.