Cracking the Code: The Role of Peripheral Nervous System Signaling in Fracture Repair.

Journal: Current osteoporosis reports
PMID: 38236511

Abstract

PURPOSE OF REVIEW: The traditionally understated role of neural regulation in fracture healing is gaining prominence, as recent findings underscore the peripheral nervous system's critical contribution to bone repair. Indeed, it is becoming more evident that the nervous system modulates every stage of fracture healing, from the onset of inflammation to repair and eventual remodeling.

Authors

  • Ashlyn J Morris
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Reginald S Parker
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Murad K Nazzal
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Roman M Natoli
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Jill C Fehrenbacher
    Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Melissa A Kacena
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. mkacena@iupui.edu.
  • Fletcher A White
    Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA. fawhite@iu.edu.

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