NAIF: A novel artificial intelligence-based tool for accurate diagnosis of stage F3/F4 liver fibrosis in the general adult population, validated with three external datasets.

Journal: International journal of medical informatics
PMID: 38395017

Abstract

OBJECTIVE: The purpose of this study was to determine the effectiveness of a new AI-based tool called NAIF (NAFLD-AI-Fibrosis) in identifying individuals from the general population with advanced liver fibrosis (stage F3/F4). We compared NAIF's performance to two existing risk score calculators, aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis-4 (Fib4).

Authors

  • Samir Hassoun
    Unità Operativa Centro Controllo Qualità e Rischio Chimico (CQRC), Azienda Ospedaliera Villa Sofia Cervello, Palermo, Italy. Electronic address: samir.dipatre.hassoun@gmail.com.
  • Chiara Bruckmann
    Unità Operativa Centro Controllo Qualità e Rischio Chimico (CQRC), Azienda Ospedaliera Villa Sofia Cervello, Palermo, Italy. Electronic address: bruckmannchiara@gmail.com.
  • Stefano Ciardullo
    Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; Department of Medicine and Surgery, School of Medicine, University of Milano-Bicocca, Monza, Italy.
  • Gianluca Perseghin
    Department of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy; Department of Medicine and Surgery, School of Medicine, University of Milano-Bicocca, Monza, Italy.
  • Fabio Marra
    Dipartimento di Medicina Sperimentale e Clinica, University of Florence, Largo Giovanni Alessandro Brambilla, 3, 50134 Firenze Italy.
  • Armando Curto
    Dipartimento di Medicina Sperimentale e Clinica, University of Florence, Largo Giovanni Alessandro Brambilla, 3, 50134 Firenze Italy.
  • Umberto Arena
    Dipartimento di Medicina Sperimentale e Clinica, University of Florence, Largo Giovanni Alessandro Brambilla, 3, 50134 Firenze Italy.
  • Francesco Broccolo
    Department of Medicine and Surgery, School of Medicine, University of Milano-Bicocca, Monza, Italy; Cerba HealthCare Italia, Milan, Italy.
  • Francesca Di Gaudio
    Unità Operativa Centro Controllo Qualità e Rischio Chimico (CQRC), Azienda Ospedaliera Villa Sofia Cervello, Palermo, Italy.

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