High-throughput microfluidic systems accelerated by artificial intelligence for biomedical applications.

Journal: Lab on a chip
PMID:

Abstract

High-throughput microfluidic systems are widely used in biomedical fields for tasks like disease detection, drug testing, and material discovery. Despite the great advances in automation and throughput, the large amounts of data generated by the high-throughput microfluidic systems generally outpace the abilities of manual analysis. Recently, the convergence of microfluidic systems and artificial intelligence (AI) has been promising in solving the issue by significantly accelerating the process of data analysis as well as improving the capability of intelligent decision. This review offers a comprehensive introduction on AI methods and outlines the current advances of high-throughput microfluidic systems accelerated by AI, covering biomedical detection, drug screening, and automated system control and design. Furthermore, the challenges and opportunities in this field are critically discussed as well.

Authors

  • Jianhua Zhou
    Department of Ultrasound, Sun Yat-sen University Cancer centre, State Key Laboratory of Oncology in South China, Collaborative Innovation centre for Cancer Medicine, Guangzhou, China.
  • Jianpei Dong
    School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. huanglu39@mail.sysu.edu.cn.
  • Hongwei Hou
    Beijing Life Science Academy, Beijing 102209, China.
  • Lu Huang
    School of Food Science and Technology, Dalian Polytechnic University, National Engineering Research Center of Seafood, Dalian 116034, PR China.
  • Jinghong Li
    Department of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China.