Despite advancements in in vitro fertilization (IVF) over the past 30 years, its outcome effectiveness remains low (20-40%). This study introduces a microfluidic-based machine learning framework to improve predictive accuracy in oocyte quality assess...
Capillary microfluidic chips (CMCs) enable passive liquid transport via surface tension and wettability gradients, making them central to point-of-care diagnostics and biomedical sensing. However, accurate analysis of capillary-driven flow experiment...
Microrobots hold substantial potential for precision medicine. However, challenges remain in balancing multifunctional cargo loading with efficient locomotion and in predicting behavior in complex biological environments. Here, we present permanent m...
The frequent global outbreaks of viral infectious diseases have significantly heightened the urgent demand for molecular testing at home. However, the labor-intensive sample preparation and nucleic acid amplification steps, along with the complexity ...
Neurotechnologies and genetic tools for dissecting neural circuit functions have advanced rapidly over the past decade although the development of complementary pharmacological methodologies has comparatively lagged. Understanding the precise pharmac...
Circulating tumor cells (CTCs) are vital indicators of metastasis and provide a non-invasive method for early cancer diagnosis, prognosis, and therapeutic monitoring. However, their low prevalence and heterogeneity in the bloodstream pose significant...
Viral hepatitis remains a major global health issue, with chronic hepatitis B (HBV) and hepatitis C (HCV) causing approximately 1 million deaths annually, primarily due to liver cancer and cirrhosis. More than 1.5 million people contract HCV each yea...
Proteins can act as suitable biomarkers for the prognosis and diagnosis of certain conditions and can help us gain an understanding of the fundamental processes that occur inside an organism. In this work, we present a fully automated machine learnin...
Annual review of analytical chemistry (Palo Alto, Calif.)
Feb 25, 2025
Understanding the biophysical properties of cells is essential for biological research, diagnostics, and therapeutics. Microfluidics enhances biophysical cell characterization by enabling precise manipulation and real-time measurement at the microsca...
Efficient separation of blood plasma and Packed Cell Volume (PCV) is vital for rapid blood sensing and early disease detection, especially in point-of-care and resource-limited environments. Conventional centrifugation methods for separation are reso...
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