Radioport: a radiomics-reporting network for interpretable deep learning in BI-RADS classification of mammographic calcification.

Journal: Physics in medicine and biology
PMID:

Abstract

Generally, due to a lack of explainability, radiomics based on deep learning has been perceived as a black-box solution for radiologists. Automatic generation of diagnostic reports is a semantic approach to enhance the explanation of deep learning radiomics (DLR).In this paper, we propose a novel model called radiomics-reporting network (Radioport), which incorporates text attention. This model aims to improve the interpretability of DLR in mammographic calcification diagnosis. Firstly, it employs convolutional neural networks to extract visual features as radiomics for multi-category classification based on breast imaging reporting and data system. Then, it builds a mapping between these visual features and textual features to generate diagnostic reports, incorporating an attention module for improved clarity.To demonstrate the effectiveness of our proposed model, we conducted experiments on a breast calcification dataset comprising mammograms and diagnostic reports. The results demonstrate that our model can: (i) semantically enhance the interpretability of DLR; and, (ii) improve the readability of generated medical reports.Our interpretable textual model can explicitly simulate the mammographic calcification diagnosis process.

Authors

  • Ting Pang
    Center of Image and Signal Processing, Faculty of Computer Science and Infomation Technology, University of Malaya, Kuala Lumpur, 50603, Malaysia; Center of Network and Information, Xinxiang Medical University, Xinxiang, 453000, PR China.
  • Jeannie Hsiu Ding Wong
    Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia. Electronic address: jeannie.wong@ummc.edu.my.
  • Wei Lin Ng
    Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia.
  • Chee Seng Chan
  • Chang Wang
    Key Laboratory of the plateau of environmental damage control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China.
  • Xuezhi Zhou
    College of Medical Engineering, Xinxiang Medical University, Xinxiang, 453000, People's Republic of China.
  • Yi Yu
    Center of Reproductive Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315100, China.