Drug-Online: an online platform for drug-target interaction, affinity, and binding sites identification using deep learning.

Journal: BMC bioinformatics
PMID: 38641811

Abstract

BACKGROUND: Accurately identifying drug-target interaction (DTI), affinity (DTA), and binding sites (DTS) is crucial for drug screening, repositioning, and design, as well as for understanding the functions of target. Although there are a few online platforms based on deep learning for drug-target interaction, affinity, and binding sites identification, there is currently no integrated online platforms for all three aspects.

Authors

  • Xin Zeng
    Electrical and Computer Engineering Department, University of California, Los Angeles, CA, 90095, USA.
  • Guang-Peng Su
    College of Mathematics and Computer Science, Dali University, Dali, 671003, China.
  • Shu-Juan Li
    Yunnan Institute of Endemic Diseases Control and Prevention, Dali, 671000, China.
  • Shuang-Qing Lv
    Institute of Surveying and Information Engineering West, Yunnan University of Applied Science, Dali, 671000, China.
  • Meng-Liang Wen
    State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, 650000, China.
  • Yi Li
    Wuhan Zoncare Bio-Medical Electronics Co., Ltd, Wuhan, China.

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