Reduction of ADC bias in diffusion MRI with deep learning-based acceleration: A phantom validation study at 3.0 T.

Journal: Magnetic resonance imaging
Published Date:

Abstract

PURPOSE: Further acceleration of DWI in diagnostic radiology is desired but challenging mainly due to low SNR in high b-value images and associated bias in quantitative ADC values. Deep learning-based reconstruction and denoising may provide a solution to address this challenge.

Authors

  • Teresa Lemainque
    Department of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany. Electronic address: tlemainque@ukaachen.de.
  • Masami Yoneyama
    Philips Japan, Konan 2-13-37, Minato-ku, Tokyo 108-8507, Japan.
  • Chiara Morsch
    Department of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
  • Elene Iordanishvili
    Department of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
  • Alexandra Barabasch
    Department of Diagnostic and Interventional Radiology, Medical Faculty, RWTH Aachen University, 52074 Aachen, Germany.
  • Maximilian Schulze-Hagen
    Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
  • Johannes M Peeters
    Philips Healthcare, Veenpluis 4-6, Building QR-0.113, 5684, Best, PC, Netherlands.
  • Christiane Kuhl
    Department of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Düsseldorf, Germany (J.S., D.B.A., S.N.); Institute of Computer Vision and Imaging, RWTH University Aachen, Pauwelsstrasse 30, 52072 Aachen, Germany (J.S., D.M.); Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany (D.T., M.P., F.M., C.K., S.N.); and Faculty of Mathematics and Natural Sciences, Institute of Informatics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany (S.C.).
  • Shuo Zhang
    Ph.D. Program in Computer Science, The City University of New York, New York, NY, United States.