Deciphering the environmental chemical basis of muscle quality decline by interpretable machine learning models.

Journal: The American journal of clinical nutrition
Published Date: May 31, 2024

Abstract

BACKGROUND: Sarcopenia is known as a decline in skeletal muscle quality and function that is associated with age. Sarcopenia is linked to diverse health problems, including endocrine-related diseases. Environmental chemicals (ECs), a broad class of chemicals released from industry, may influence muscle quality decline.

Authors

  • Zhen Feng
    Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Ying'ao Chen
    Postgraduate Training Base Alliance of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, People's Republic of China.
  • Yuxin Guo
    Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
  • Jie Lyu

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