PlantMine: A Machine-Learning Framework to Detect Core SNPs in Rice Genomics.

Journal: Genes
Published Date:

Abstract

As a fundamental global staple crop, rice plays a pivotal role in human nutrition and agricultural production systems. However, its complex genetic architecture and extensive trait variability pose challenges for breeders and researchers in optimizing yield and quality. Particularly to expedite breeding methods like genomic selection, isolating core SNPs related to target traits from genome-wide data reduces irrelevant mutation noise, enhancing computational precision and efficiency. Thus, exploring efficient computational approaches to mine core SNPs is of great importance. This study introduces PlantMine, an innovative computational framework that integrates feature selection and machine learning techniques to effectively identify core SNPs critical for the improvement of rice traits. Utilizing the dataset from the 3000 Rice Genomes Project, we applied different algorithms for analysis. The findings underscore the effectiveness of combining feature selection with machine learning in accurately identifying core SNPs, offering a promising avenue to expedite rice breeding efforts and improve crop productivity and resilience to stress.

Authors

  • Kai Tong
    School of Biological Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
  • Xiaojing Chen
    Department of Computer Science and Engineering, University of California, Riverside, CA, USA.
  • Shen Yan
    Center for Data Science, Peking University, China. Electronic address: yanshen@pku.edu.cn.
  • Liangli Dai
    School of Biological Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
  • Yuxue Liao
    School of Biological Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
  • Zhaoling Li
    School of Biological Engineering, Sichuan University of Science & Engineering, Yibin 644000, China.
  • Ting Wang
    CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.