AI-assisted capsule endoscopy reading in suspected small bowel bleeding: a multicentre prospective study.

Journal: The Lancet. Digital health
Published Date:

Abstract

BACKGROUND: Capsule endoscopy reading is time consuming, and readers are required to maintain attention so as not to miss significant findings. Deep convolutional neural networks can recognise relevant findings, possibly exceeding human performances and reducing the reading time of capsule endoscopy. Our primary aim was to assess the non-inferiority of artificial intelligence (AI)-assisted reading versus standard reading for potentially small bowel bleeding lesions (high P2, moderate P1; Saurin classification) at per-patient analysis. The mean reading time in both reading modalities was evaluated among the secondary endpoints.

Authors

  • Cristiano Spada
    Endoscopia Digestiva e Gastroenterologia, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Università Cattolica del Sacro Cuore, Roma, Italy. Electronic address: cristianospada@gmail.com.
  • Stefania Piccirelli
    Endoscopia Digestiva e Gastroenterologia, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Università Cattolica del Sacro Cuore, Roma, Italy.
  • Cesare Hassan
    Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome, Italy.
  • Clarissa Ferrari
    Unit of Research and Clinical Trials, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
  • Ervin Toth
    Department of Gastroenterology, Skåne University Hospital, Malmö Lund University, Malmö, Sweden.
  • Begoña González-Suárez
    Hospital Clínic of Barcelona, Endoscopy Unit, Gastroenterology Department, Barcelona, Spain.
  • Martin Keuchel
    Agaplesion Bethesda Krankenhaus Bergedorf, Academic Teaching Hospital of the University of Hamburg, Clinic for Internal Medicine, Hamburg, Germany.
  • Marc McAlindon
    Sheffield Teaching Hospitals NHS Trust, Academic Department of Gastroenterology and Hepatology, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
  • Ádám Finta
    Endo-Kapszula Health Centre and Endoscopy Unit, Department of Gastroenterology, Székesfehérvár, Hungary.
  • András Rosztóczy
    University of Szeged, Department of Internal Medicine, Szeged, Hungary.
  • Xavier Dray
    Sorbonne University, Department of Hepato-Gastroenterology, APHP, Saint Antoine Hospital, Paris, France; ETIS, Université de Cergy-Pontoise, ENSEA, CNRS, Cergy-Pontoise Cedex, France.
  • Daniele Salvi
    Department of Medicine, Gastroenterology and Endoscopy, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Maria Elena Riccioni
    Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Digestive Endoscopy Unit, Rome, Italy.
  • Robert Benamouzig
    Hopital Avicenne, APHP, Bobigny, France.
  • Amit Chattree
    South Tyneside and Sunderland NHS Foundation Trust, Gastroenterology, Stockton-on-Tees, UK.
  • Adam Humphries
    St Mark's Hospital and Academic Institute, Department of Gastroenterology, Middlesex, UK.
  • Jean-Christophe Saurin
    Department of Hepato-gastroenterology, E. Herriot Hospital, Hospices civils de Lyon, Lyon, France.
  • Edward J Despott
    Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London Institute for Liver and Digestive Health, Hampstead, London, United Kingdom.
  • Alberto Murino
    Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London Institute for Liver and Digestive Health, Hampstead, London, United Kingdom; Department of Gastroenterology, Cleveland Clinic London, London, United Kingdom.
  • Gabriele Wurm Johansson
    Skåne University Hospital, Lund University, Department of Gastroenterology, Malmö, Sweden.
  • Antonio Giordano
    Hospital Clínic of Barcelona, Endoscopy Unit, Gastroenterology Department, Barcelona, Spain.
  • Peter Baltes
    Agaplesion Bethesda Krankenhaus Bergedorf, Academic Teaching Hospital of the University of Hamburg, Clinic for Internal Medicine, Hamburg, Germany.
  • Reena Sidhu
    Sheffield Teaching Hospitals NHS Trust, Academic Department of Gastroenterology and Hepatology, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
  • Milan Szalai
    Endo-Kapszula Health Centre and Endoscopy Unit, Department of Gastroenterology, Székesfehérvár, Hungary.
  • Krisztina Helle
    University of Szeged, Department of Internal Medicine, Szeged, Hungary.
  • Artur Nemeth
    Skåne University Hospital, Lund University, Department of Gastroenterology, Malmö, Sweden.
  • Tanja Nowak
    Medical Affairs, Hamburg, Germany.
  • Rong Lin
    College of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, China.
  • Guido Costamagna
    Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.