Machine Learning and External Validation of the IDENTIFY Risk Calculator for Patients with Haematuria Referred to Secondary Care for Suspected Urinary Tract Cancer.

Journal: European urology focus
PMID:

Abstract

BACKGROUND: The IDENTIFY study developed a model to predict urinary tract cancer using patient characteristics from a large multicentre, international cohort of patients referred with haematuria. In addition to calculating an individual's cancer risk, it proposes thresholds to stratify them into very-low-risk (<1%), low-risk (1-<5%), intermediate-risk (5-<20%), and high-risk (≥20%) groups.

Authors

  • Sinan Khadhouri
    School of Medicine, University of St Andrews, St Andrews, UK; British Urological Researchers in Surgical Training (BURST), London, UK. Electronic address: sinan.khadhouri@doctors.org.uk.
  • Artsiom Hramyka
    School of Computer Science, University of St Andrews, St Andrews, UK.
  • Kevin Gallagher
    British Urological Researchers in Surgical Training (BURST), London, UK; Institute of Cancer and Genetics, University of Edinburgh, Edinburgh, UK; Division of Surgery and Interventional Science, University College London, London, UK.
  • Alexander Light
    Division of Urology, Department of Surgery, University of Cambridge, UK.
  • Simona Ippoliti
    British Urological Researchers in Surgical Training (BURST), London, UK; Department of Paediatric Surgery, Hull Royal Infirmary, Hull University Teaching Hospitals, Hull, UK.
  • Marie Edison
    British Urological Researchers in Surgical Training (BURST), London, UK; Department of Urology, Chelsea and Westminster Hospital, London, UK.
  • Cameron Alexander
    British Urological Researchers in Surgical Training (BURST), London, UK; Luton and Dunstable University Hospital, Luton, UK.
  • Meghana Kulkarni
    Department of Urology, Guy's Hospital, London, UK.
  • Eleanor Zimmermann
    British Urological Researchers in Surgical Training (BURST), London, UK; Department of Urology, Southmead Hospital, Bristol, UK.
  • Arjun Nathan
    Urology Department, Addenbrooke's Hospital, Cambridge, UK. arjun.nathan.11@ucl.ac.uk.
  • Luca Orecchia
    Urology Unit, Department of Surgical Sciences, Tor Vergata University Hospital, University of Rome Tor Vergata, Rome, Italy.
  • Ravi Banthia
    University Hospital Coventry Warwickshire, Coventry, UK.
  • Pietro Piazza
    Division of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
  • David Mak
    Royal Wolverhampton Hospitals, Wolverhampton, UK.
  • Nikolaos Pyrgidis
    Department of Urology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Prabhat Narayan
    Royal Berkshire Hospital, Reading, UK.
  • Pablo Abad Lopez
    Hospital Clinico San Carlos, Madrid, Spain.
  • Faisal Nawaz
    College of Medicine Mohammed Bin Rashid University of Medicine and Health Sciences Dubai UAE.
  • Trung-Thanh Tran
    Department of Surgery, Hanoi Medical University, Hanoi, Vietnam; Department of Urology, Hanoi Medical University Hospital, Hanoi, Vietnam.
  • Francesco Claps
    University of Trieste, Trieste, Italy.
  • Donnacha Hogan
    Mercy University Hospital, Cork, Ireland.
  • Juan Gomez Rivas
    Department of Urology, Clinico San Carlos University Hospital, Madrid, Spain.
  • Santiago Alonso
    Urologia-Hospital Clinico San Carlos, Madrid, Spain.
  • Ijeoma Chibuzo
    Stepping Hill Hospital, Stockport, UK.
  • Beatriz Gutierrez Hidalgo
    Clinico San Carlos Hospital, Madrid, Spain.
  • Jessica Whitburn
    Oxford University Hospitals, Oxford, UK.
  • Jeremy Teoh
    S.H. Ho Urology Center, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
  • Gautier Marcq
    Urology Department, Claude Huriez Hospital, CHU Lille, Lille, France; CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-U1277 - CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, University Lille, Lille, France.
  • Alexandra Szostek
    Urology Department, Claude Huriez Hospital, CHU Lille, Lille, France.
  • Jasper Bondad
    Southend University Hospital, Southend-on-Sea, Essex, UK.
  • Petros Sountoulides
    Department of Urology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Tom Kelsey
    School of Computer Science, University of St. Andrews, St. Andrews, United Kingdom.
  • Veeru Kasivisvanathan
    Department of Urology, Guy's Hospital, London, UK; Division of Surgery, University College London, London, UK.