Multi-modal segmentation with missing image data for automatic delineation of gross tumor volumes in head and neck cancers.

Journal: Medical physics
Published Date:

Abstract

BACKGROUND: Head and neck (HN) gross tumor volume (GTV) auto-segmentation is challenging due to the morphological complexity and low image contrast of targets. Multi-modality images, including computed tomography (CT) and positron emission tomography (PET), are used in the routine clinic to assist radiation oncologists for accurate GTV delineation. However, the availability of PET imaging may not always be guaranteed.

Authors

  • Yao Zhao
    School of Environmental Science and Engineering, Shaanxi University of Science and Technology, Xi'an 170021, China.
  • Xin Wang
    Key Laboratory of Bio-based Material Science & Technology (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
  • Jack Phan
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Xinru Chen
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX 77030, United States.
  • Anna Lee
    Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • Cenji Yu
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX 77030, United States.
  • Kai Huang
  • Laurence E Court
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tinsu Pan
    Department of Imaging Physics, M.D. Anderson Cancer Center, University of Texas, Houston, Texas, USA.
  • He Wang
    Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, China International Neuroscience Institute, Beijing, China.
  • Kareem Abdul Wahid
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Abdalah S R Mohamed
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Mohamed Naser
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Clifton D Fuller
    Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Jinzhong Yang
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.