Digital twins: reimagining the future of cardiovascular risk prediction and personalised care.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese
PMID:

Abstract

The rapid evolution of highly adaptable and reusable artificial intelligence models facilitates the implementation of digital twinning and has the potential to redefine cardiovascular risk prevention. Digital twinning combines vast amounts of data from diverse sources to construct virtual models of an individual. Emerging artificial intelligence models, called generalist AI, enable the processing of different types of data, including data from electronic health records, laboratory results, medical texts, imaging, genomics, or graphs. Among their unprecedented capabilities are an easy adaptation of a model to previously unseen medical tasks and the ability to reason and explain output using precise medical language derived from scientific literature, medical guidelines, or knowledge graphs. The proposed combination of a digital twinning approach with generalist AI is a path to accelerate the implementation of precision medicine and enhance early recognition and prevention of cardiovascular disease. This proposed strategy may extend to other domains to advance predictive, preventive, and precision medicine and also boost health research discoveries.

Authors

  • Katarzyna Dziopa
    Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, Netherlands; Institute of Health Informatics, University College London, London, United Kingdom; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom. Electronic address: k.d.dziopa@amsterdamumc.nl.
  • Karim Lekadir
    Information and Communication Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain.
  • Pim van der Harst
    Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
  • Folkert W Asselbergs