Examining the Most Important Risk Factors for Predicting Youth Persistent and Distressing Psychotic-Like Experiences.

Journal: Biological psychiatry. Cognitive neuroscience and neuroimaging
Published Date: Jun 5, 2024

Abstract

BACKGROUND: Persistence and distress distinguish more clinically significant psychotic-like experiences (PLEs) from those that are less likely to be associated with impairment and/or need for care. Identifying risk factors that identify clinically relevant PLEs early in development is important for improving our understanding of the etiopathogenesis of these experiences. Machine learning analyses were used to examine the most important baseline factors distinguishing persistent distressing PLEs.

Authors

  • Nicole R Karcher
    Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri. Electronic address: nkarcher@wustl.edu.
  • Aristeidis Sotiras
    Department of Radiology and Institute of Informatics, Washington University in St. Luis, St. Luis, MO63110, USA.
  • Tara A Niendam
    Department of Psychiatry and Behavioral Sciences, University of California Davis, Davis, California.
  • Elaine F Walker
    Department of Psychiatry, Emory University, Atlanta, GA, United States.
  • Joshua J Jackson
    Department of Psychological and Brain Sciences, Washington University in St Louis, St. Louis, Missouri.
  • Deanna M Barch
    Department of Psychological & Brain Sciences, School of Arts & Sciences, Washington University in St. Louis, St. Louis, Missouri.

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