Application of improved glomerular filtration rate estimation by a neural network model in patients with neurogenic lower urinary tract dysfunction.

Journal: Clinical nephrology
PMID:

Abstract

BACKGROUND: Previous studies have indicated that creatinine (Cr)-based glomerular filtration rate (GFR) estimating equations - including the new Chronic Kidney Disease Epidemiology creatinine (CKD-EPI) equation without race and the estimated glomerular filtration rate (eGFR) equation developed for the Chinese population - displayed suboptimal performance in patients with neurogenic lower urinary tract dysfunction (NLUTD), which limited their clinical application for detecting changes in GFR levels in all cohorts.

Authors

  • Ying-Chun Ma
  • Yang Xie
    Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, 5325 Harry Hines Blvd, Dallas, TX, 75390, USA.
  • Limin Liao
    Department of Urology, School of Rehabilitation, China Rehabilitation Research Center, Beijing Bo'ai Hospital, Capital Medical University, Beijing, China.