Chronic kidney disease (CKD) is a major public health problem worldwide associated with cardiovascular disease, renal failure, and mortality. To effectively address this growing burden, innovative solutions to management are urgently required. We co...
BACKGROUND: Chronic kidney disease (CKD) is a global health concern characterised by irreversible renal damage that is often assessed using invasive renal biopsy. Accurate evaluation of interstitial fibrosis and tubular atrophy (IFTA) is crucial for ...
BACKGROUND: Patients with chronic kidney disease (CKD) are considered the primary population at risk for post-contrast acute kidney injury (PC-AKI), yet there are few predictive tools specifically designed for this vulnerable population.
International journal of molecular sciences
40076962
Cell-mediated immunity and chronic inflammation are hallmarks of chronic kidney disease (CKD). Growth differentiation factor 15 (GDF15) is a marker of inflammation and an integrative signal in stress conditions. Epidermal growth factor (EGF) is a tub...
Diabetic kidney disease (DKD) is a serious healthcare dilemma. Nonetheless, the interplay between the functional capacity of gut microbiota and their host remains elusive for DKD. This study aims to elucidate the functional capability of gut microbio...
BACKGROUND: Chronic kidney disease (CKD) is a major global public health issue, with a steadily increasing incidence. Urinary protein detection serves as a crucial indicator for the diagnosis, monitoring and management of CKD. However, current method...
Chronic kidney disease (CKD) is a global public health concern, and the timely detection of the disease is priceless. Most of the classical machine learning models have the major drawbacks of being unsophisticated, non-robust, and non-accurate. This ...
OBJECTIVE: Kidney fibrosis is a key pathological feature in the progression of chronic kidney disease (CKD), traditionally diagnosed through invasive kidney biopsy. This study aimed to develop and validate a noninvasive, multi-center predictive model...
PURPOSE: Clinical management of pediatric chronic kidney disease requires estimation of glomerular filtration rate (eGFR). Currently, eGFR is determined by two endogenous markers measured in blood: serum creatine (SCr) and cystatin C (CysC). Machine ...
Chronic kidney disease-mineral bone disorder is a common complication in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), and it increases the risk of osteoporosis and fractures. This study aimed to develop predictive m...