AI Medical Compendium Journal:
Journal of bioinformatics and computational biology

Showing 71 to 73 of 73 articles

Protein secondary structure prediction improved by recurrent neural networks integrated with two-dimensional convolutional neural networks.

Journal of bioinformatics and computational biology Oct 1, 2018
Protein secondary structure prediction (PSSP) is an important research field in bioinformatics. The representation of protein sequence features could be treated as a matrix, which includes the amino-acid residue (time-step) dimension and the feature ...
Neural Networks, Computer Deep Learning Computational Biology Proteins Databases, Protein Protein Structure, Secondary
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A systematic exploration of [Formula: see text] cutoff ranges in machine learning models for protein mutation stability prediction.

Journal of bioinformatics and computational biology Oct 1, 2018
Discerning how a mutation affects the stability of a protein is central to the study of a wide range of diseases. Mutagenesis experiments on physical proteins provide precise insights about the effects of amino acid substitutions, but such studies ar...
Neural Networks, Computer Machine Learning Algorithms Computational Biology Support Vector Machine Proteins Mutation Protein Stability Random Allocation Amino Acid Substitution
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GI-SVM: A sensitive method for predicting genomic islands based on unannotated sequence of a single genome.

Journal of bioinformatics and computational biology Feb 1, 2016
Genomic islands (GIs) are clusters of functionally related genes acquired by lateral genetic transfer (LGT), and they are present in many bacterial genomes. GIs are extremely important for bacterial research, because they not only promote genome evol...
Genomics Support Vector Machine Sequence Analysis, DNA Pseudomonas aeruginosa Salmonella typhi Genomic Islands Genome, Bacterial Gene Transfer, Horizontal Corynebacterium diphtheriae
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