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Gene Transfer, Horizontal

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Pre_GI: a global map of ontological links between horizontally transferred genomic islands in bacterial and archaeal genomes.

Database : the journal of biological databases and curation
The Predicted Genomic Islands database (Pre_GI) is a comprehensive repository of prokaryotic genomic islands (islands, GIs) freely accessible at http://pregi.bi.up.ac.za/index.php. Pre_GI, Version 2015, catalogues 26 744 islands identified in 2407 ba...

GI-SVM: A sensitive method for predicting genomic islands based on unannotated sequence of a single genome.

Journal of bioinformatics and computational biology
Genomic islands (GIs) are clusters of functionally related genes acquired by lateral genetic transfer (LGT), and they are present in many bacterial genomes. GIs are extremely important for bacterial research, because they not only promote genome evol...

Deep learning for HGT insertion sites recognition.

BMC genomics
BACKGROUND: Horizontal Gene Transfer (HGT) refers to the sharing of genetic materials between distant species that are not in a parent-offspring relationship. The HGT insertion sites are important to understand the HGT mechanisms. Recent studies in m...

Identifying genomic islands with deep neural networks.

BMC genomics
BACKGROUND: Horizontal gene transfer is the main source of adaptability for bacteria, through which genes are obtained from different sources including bacteria, archaea, viruses, and eukaryotes. This process promotes the rapid spread of genetic info...

ICEO, a biological ontology for representing and analyzing bacterial integrative and conjugative elements.

Scientific data
Bacterial integrative and conjugative elements (ICEs) are highly modular mobile genetic elements critical to the horizontal transfer of antibiotic resistance and virulence factor genes. To better understand and analyze the ongoing increase of ICEs, w...

Invariant transformers of Robinson and Foulds distance matrices for Convolutional Neural Network.

Journal of bioinformatics and computational biology
The evolutionary histories of genes are susceptible of differing greatly from each other which could be explained by evolutionary variations in horizontal gene transfers or biological recombinations. A phylogenetic tree would therefore represent the ...

Current state and future prospects of Horizontal Gene Transfer detection.

NAR genomics and bioinformatics
Artificial intelligence (AI) has been shown to be beneficial in a wide range of bioinformatics applications. Horizontal Gene Transfer (HGT) is a driving force of evolutionary changes in prokaryotes. It is widely recognized that it contributes to the ...

MOSTPLAS: a self-correction multi-label learning model for plasmid host range prediction.

Bioinformatics (Oxford, England)
MOTIVATION: Plasmids play an essential role in horizontal gene transfer, aiding their host bacteria in acquiring beneficial traits like antibiotic and metal resistance. There exist some plasmids that can transfer, replicate, or persist in multiple or...