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Amino Acyl-tRNA Synthetases

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Uncovering substrate specificity determinants of class IIb aminoacyl-tRNA synthetases with machine learning.

Journal of molecular graphics & modelling
Specific amino acid (AA) binding by aminoacyl-tRNA synthetases (aaRSs) is necessary for correct translation of the genetic code. Sequence and structure analyses have revealed the main specificity determinants and allowed a partitioning of aaRSs into ...